Syllabus contribution - ISMRM 22 Annual Scientific Meeting, Milan, May 2014 Session: An Update on fMRI Title: Clinical Applications of fMRI: from Presurgical Planning to Functional Connectivity

Highlights: • Neurosurgical decision-making critically revolves around current and potential Quality of Life. • Greater understanding of key functional systems in the brain, and their adaptive potential, dramatically increases the relevance of brain mapping techniques to optimise individual patient outcomes. • fMRI allows mapping of key functional regions and related networks that can assist the clinician in determining surgical risks and boundaries, predicting cognitive outcome/recovery, and selecting patients for surgery previously considered inoperable. • Improved knowledge of how functional systems are organised and interact, based on task, resting and diffusion MRI, promises a great step towards individualized medicine.